Outline the effect of the following mutations:
TAG-> TAT
TAC-> TCC
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Answer:
TAG-> TAT >> sense mutation
TAC-> TCC >> missense mutation
Explanation:
A sense mutation is a type of mutation that changes a stop codon into a sense codon, thus producing an elongated protein. The TAG codon (UAG in the RNA) is a stop codon, while TAT (UAU) encodes for tyrosine, thereby TAG-> TAT is a sense mutation. On the other hand, a missense mutation is a type of point mutation where a single nucleotide change generates a new codon which encodes a different amino acid. In this case, the TAC codon (UAC) encodes for tyrosine, while TCC (UCC) codon encodes for serine, and therefore TAC-> TCC is a missense mutation (Tyr to Ser mutation).