Most people do not realize that the lack of a gene can often result in a trait, such as the inability to digest milk because the cell doesn't express a gene that codes for the enzyme lactase. The failure of which biomolecule results in the missing gene that leads to the inability to digest milk?
Enzymes (protein) are responsible for proofreading the replicated DNA sequences and fixing any mistake. The failure of that, brought about this genetic fault that gets passed down generations.