Griffith showed that cells contain a transforming factor.
What is Griffith's experiment?
- He worked on the pneumonia causing bacteria, Streptococcus pneumoniae.
- He found that this bacteria has two colonies: smooth colonies (S strain) and rough colonies (R strain).
- When mice were infected with S strain, they die from pneumonia whereas mice infected with R strain will survive as they do not develop pneumonia.
- The bacteria was the killed by heating. When mice were infected with heat-killed S strain, they survive as they do not develop pneumonia whereas when mice were infected with heat-killed S strain + live R strain, they die.
- It was observed that the R strain has been transformed by heat-killed S strain.
- It states that some "transforming principle" has enabled heat-killed S strain to transfer its virulent properties to R strain.
Hence, the correct option is B. He showed that cells contain a transforming factor.
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