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Now that you have come up with an equation that describes the relationship between amounts of different nucleotide bases in DNA, can you use it to predict the amounts of all four nucleotide bases when you only know the amount of one type of base? Approximately 21% of the human genome is comprised of nucleotides containing C. Given this information, calculate the percentage of the human genome that is comprised of nucleotides containing G, T, and A.

a. _____% of the human genome is comprised of G.
b. _____% of the human genome is comprised of T.
c. _____% of the human genome is comprised of A.

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Answer:

a. 21% G

b. 29% T

c. 29% A

Explanation:

Based on Chargaff's rule, we know that A = T and C = G.

.21 C => .21 G

.21 + .21 = .42

So we know all the C and G is .42. So what's left must be the A and T.

1 - .42 = .58

There's .58 A and T, so divide that in half, because they're equal amounts.

.58/2 = .29

.29 A => .29 T

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