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Which of the following is/are true about eukaryotic transcription?

A) RNA polymerases bind directly to the core promoter (TATA box)

B) Transcription factors are required for RNA polymerase ll-dependent transcription

C) RNA polymerase ll transcribes the protein-coding genes

D) Poly-A tail is the last part of transcript synthesis by RNA polymerase ll.

E) rho factor participates in transcription termination

Respuesta :

The answer is D I believe. 20 characters

Answer:

  • Option B is true (Transcription factors are required for RNA polymerase ll-dependent transcription)

Explanation:

Option B is correct because many different transcription factors are involved in the eukaryotic transcription, particularly genes transcribe by RNA polymerase II. TFIID, A, B, F, E, and H are general or basal transcription factors of human.

Option A is wrong because RNA polymerase II first bind with the general transcription factor, TFIID. TFIID recognise the TATA box and forms a platform for TFIIB binding.

Option C is wrong because RNA polymerase II transcribe protein coding genes but it also transcribe small nuclear RNAs (snRNAs).

Option D is incorrect because transcription of poly-A tail is synthesized by template-independent RNA polymerase called poly(A) polymerase.

Option E is also incorrect- rho factor or rho-dependent termination is used by bacterial transcription termination process.

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