The Mississippi River would require the use of a large-scale model. The correct option is D.
What is a model?
A model is an artificial representation of a big thing or a program. Models can be used to teach people how actually things look. Those things or objects can not be seen in real life.
The Mississippi River is the second-longest river in the United States. It crosses many states of the United States. It is known for its second-largest drainage system.
An atom, car engine, or frog heart is a small thing that will require small models. But the Mississippi River is the largest river, so it will need a big model for its representation. So the Mississippi River would be correct for the big model.
Thus, the correct option is D. The Mississippi River.
To learn more about the model, refer to the below link:
https://brainly.com/question/19426210
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