The scientists hope to test Sepin‑1 in clinical trials with human cancer patients. The scientists claim that one way to test the efficacy of the Sepin‑1 treatment will be to obtain periodic samples of the patients’ cancer cells and determine the percent of cells in metaphase. Provide reasoning to support the scientists’ claim.

The reasoning behind this relies on the separate function, as we said, it works by cleaving the complex that attaches the sister chromatids together, by doing so mitosis can continue and segregate the sister chromatids. This separase action is what allows the division to pass from metaphase to anaphase. If the separase inhibition is successful, we expect to find cancer cells that were not able to pass to anaphase, thus we expect cells stuck in metaphase.

kasliwalalvi24 kasliwalalvi24 · Answer 2 · 2021-10-26T11:28:12+02:00

Cancer can be caused due to drugs, environmental, or genetic causes. Cancer is the abnormal growth of cells.

Sepin-1 is used to treat cancer as stops the cell growth in metaphase.

Sepin-1 is a compound that inhibits the activity of separase and the growth of cancer cells. The compound causes the apoptosis of the cell.

The enzyme separase is responsible for the hydrolyzing cohesin to trigger the cells to enter the anaphase.

The reasons on scientist's claim are:

Sepin-1 use on human cancer cells can be done to prevent the growth of cells.
The compound inhibits the activity of separase, the enzyme responsible for the cell to enter in the anaphase.
The periodic samples of the human cancer cells can be obtained from the effect of sepin-1.
The cells will be stuck in metaphase if the functioning of sepin-1 will be successful.

Therefore, the sepin-1 can inhibit separase and prevent the growth of cancer cells.

To know more about sepin-1 and cancer cells, refer to the following link:

https://brainly.com/question/15606182