Niclosamide prevents ATP generation in mitochondria. You would expect this drug to be effective against _____. a) Mycobacterium tuberculosis.b) Viruses. c) Gram-positive bacteria.d) Fungi. e) Gram-negative bacteria.
Niclosamide is an anti-helminth drug. It works by inhibiting ATP generation in the mitochondria. ATP which is a major source of energy for cellular organisms is deficient thereby hindering or stopping metabolic processes and then death. Helminths in which Niclosamide is effective against include Pin worm, Round wo,Beef tapeworm( Taenia saginata) etc. The drug is taken orally.
