In eukaryotic cells, ribosomes are found both free in the cytosol and attached to the endoplasmic reticulum (ER). Proteins produced on the attached ribosomes are delivered to the ER, while proteins produced on free ribosomes are delivered to the cytosol. Briefly explain in one or two sentences the two processes in terms of the following:

1. ONE ultimate destination of a protein produced on an attached ribosome, and ONE general function of the protein (You do not need to identify the specific protein.)

2. ONE ultimate destination of a protein produced on a free ribosome, and ONE general function of the protein (You do not need to identify the specific protein.)

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Answer:

1. Protein synthesis on attached ribosomes:

Destination:  cell membrane.

One general function : to be a surface receptor.

2. On free ribosomes- destination:  cytosol

One general function: microfilaments.

Explanation:

Proteins are synthesized by the process known as translation. Translation occurs by ribosomes as they can be attached with endoplasmic reticulum or they can be free in the cytosol.

Protein is synthesized according to the sequence of nucleotide on mRNA.

Newly synthesized protein contain signals  sequence which targets then for their final destination.

1. ONE ultimate destination of a protein produced on an attached ribosome:  These proteins, after synthesis enter into ER and then according to the signal sequence, they reach to their final destination.

Example: cell membrane.

One general function of the protein -  to be a surface receptor

2. One ultimate destination of a protein produced on a free ribosome: cytosol

One general function of the protein: microfilaments

One ultimate destination for a protein produced on an attached ribosome, and one general function of the protein are;

  • Cell membrane is known as the destination
  • Its duty or function is to be a surface receptor.

One ultimate destination for a protein produced on an unattached ribosome, and one general function of the protein is that

  • Its destination is the cytosol (cytoplasm)
  • It is known to function mainly to make microfilaments.

Attached ribosomes is known to produce proteins that are meant for specific purposes outside the cell. e.g. The digestive enzymes used in the gut.  They are known to make or produce hormones and certain cell membrane proteins that act as surface receptor.

Free, or detached, ribosomes often go or float within the cell's intracellular fluid, or cytoplasm. They are known to be free in their movement around anywhere other than the nucleus and other organelles.

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