When the blood becomes acidic (acidosis) and bicarbonate ions have been depleted, new bicarbonate ions must be generated in the plasma. Which of the following is NOT a means for replenishing bicarbonate ions?

a.Bicarbonate ions are reclaimed by tubular reabsorption.
b.Ammonium ions are excreted in urine.
c.Glutamine is metabolized by deamination, oxidation, and acidification.
d.Buffered hydrogen ions are excreted in urine.

Respuesta :

Answer:

c. Glutamine is metabolized by deamination, oxidation, and acidification.

Explanation:

Bicarbonate ions are an important part of bicarbonate buffer system which helps to maintain the pH of blood. Whenever blood starts to become acidic, bicarbonate ions increase to neutralize its effect. Their concentration can be increased by many mechanisms, for example tubular reabsorption.

However, glutamine catabolism does not replenish bicarbonate ions, in fact it does the exact opposite. Kidney generates ammonium ions by catabolism of glutamine which are excreted in the urine. This process also facilitates the excretion of bicarbonate ions.

When there is the overproduction of acids in the blood or due to loss in bicarbonate ions from the blood system is called acidosis.  This affects the respiratory system and breathing becomes difficult.

The correct answer is:

Option c. Glutamine is metabolized by deamination, oxidation, and acidification.

This can be explained as:

  • In the buffer system, the bicarbonate plays a major role in maintaining the pH balance.

  • In the increased conditions of the acid influx in the blood is maintained by the release of bicarbonate ions to neutralize the effect.

  • The bicarbonate can be replenished by tubular re-absorption.

  • In glutamine catabolism, the bicarbonates are released freely and are not replenished.

  • Glutamine is catabolized into ammonium ions and is excreted into the excretory system.

Therefore, oxidation, deaminations and acidification of glutamine do not replenish the bicarbonate ions.

To learn more about blood acidosis follow the link:

https://brainly.com/question/9424833

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