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Which of the following defects is most likely to be found in yeast cells with a dramatically increased rate of genomic mutation per cell cycle?

A) Activation of a G1/S DNA damage checkpoint in the absence of DNA damage.
B) Activation of a G1 restriction point checkpoint despite adequate cell size and nutrient supply.
C) A nonsense mutation within a DNA replication polymerase.
D) An inactivating mutation within a gene encoding an essential component of the unreplicated DNA checkpoint.
E) Activation of a G2/M DNA damage checkpoint in the absence of DNA damage.

Respuesta :

yemmy

Answer:

D

Explanation

In each cell cycle, what is responsible for an increased rate of genomic mutation is what happens in a gene that represent DNA damage checkpoint components. The reason being that they are the regulators that blocks and allows to ensure that the cell can proceed to the next cell division stage when a DNA damage occurs. They also lose their ability to get mutated which is a defect that multiplies in each cell cycle

Hence,

Option D An inactivating mutation within a gene encoding an essential component of the unreplicated DNA checkpoint

is the right answer to this question

albertaebisindou

Answer:

The correct answer is option D.

D) An inactivating mutation within a gene encoding an essential component of the unreplicated DNA checkpoint.

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