Respuesta :

Answer: Option D). a mutation.

Explanation:

Mutation is the change in the genetic composition of the cell. This change in a gene can be due to

- spontaneous change in nitrogenous base

- error during replication i.e incorrect copying of DNA template strand

- damage to DNA by ionizing radiation such as X-rays

- damage to DNA by heavy metals such as cadmium, lead etc

Thus, mutation is the answer.