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In addition to activating protein kinase C, the phospholipid derived membrane by-product, __________, activates the _______ pathway that involves a cascade of kinase activation culminating in activation of the AP-1 transcription factor.

Fill in the blanks using the words and terms provided below.

ITAM CD40 RAS IP3
CD4 DAG calcineurin Ca2+
CD3 complex PAMPs CD8 PLC-\gammaγ
CDR calmodulin NF-AT NF-\kappaκB
I\kappaκB IgA IgG IgD
IgE IgM CD40L ZAP70
western blot IL-4 IL-2 FoxP3
RSS ZAP70 RER Igaa/Ig\betaβ
TGF-\betaβ TLRs MHC class I MHC class II
perforin TAP RAG granzymes
epitope FACS ELISA TNF-\alphaα

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okpalawalter8

Complete Question

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Answer:

In addition to activating protein kinase C, the phospholipid derived membrane by-product, DAG (Diacylglycerol), activates the RAS pathway that involves a cascade of kinase activation culminating in activation of the AP-1 transcription factor.

Step-by-step explanation:

DAG is known to activate PKC enzymes which are involved in several signal transduction cascades and DAG is also known to activate RAS, a GTP binding protein which in turn stimulates protein kinases involved in various growth factor responses.

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