A patient presents with sudden onset of gross hematuria, proteinuria and hypertension. In assessing this patient, what statement best supports the importance for the nurse to assess the presence of throat discomfort over the past two weeks? 1. Streptococcal pharyngitis can induce glomerulonephritis. 2. Hemolytic uremic syndrome (HUS) initially presents with pharyngitis. 3. Hematuria is the primary indicator that the patient has nephrotic syndrome caused by E. coli. 4. Throat discomfort is an indication of edema which is the primary cause of nephrotic syndrome.