Answer: Progression
Explanation:
Carcinogenesis can be defined as the formation of cancerous cell in the body. The normal cells of the body gets converted into oncogenes.
Carcinogenesis can be caused due to any of the following factors. These factors are physical, biological and genetic factors.
The stages of carcinogenesis are initiation, promotion and progression. In the stage of progression is irreversible karyotipic instability and growth of malignant tumor.