Explanation:
Environmental contamination reduces total testosterone oxido-reductase activity in females.- True
Enzymes are proteins which catalyze reactions by acting on substrates in order to speed up reactions- like the breakdown of large polysaccharides by amylase. Here, the enzyme testosterone oxi-reductase facilitates the of testosterone to the androgen DHT. Enzyme specificity is affected by pH, temperature and the presence of inhibitors.
In temperatures beyond its optimal range, these may undergo changes to its physical structure called denaturation; when denatured, enzymes lose their ability to bind specifically to their substrate -i.e. substrate binding specificity is lost. Testosterone would no longer be able to bind to the active site, and thus would not be converted.
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