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Which of the following is true?

a. Uncontrolled cell growth alone is sufficient for the development of cancers.
b. Mutations that inactivate tumor suppressor genes are important in cancer.
c. Cancer is a single disease with one underlying molecular cause.
d. Cancer is a single disease resulting from a common set of mutations.

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Answer:

b. Mutations that inactivate tumor suppressor genes are important in cancer.

Explanation:

Most cancers have inactivating mutations in one or more proteins that normally,Cancer can result from expression of mutant forms of these proteins: growth factors and mutation in only one of the two alleles is sufficient for induction of cancer, the cells from tumors caused by these viruses is near the c-myc gene.