For the 1st question- They include strong prescription pain relievers, such as oxycodone, hydrocodone, fentanyl, and tramadol. The illegal drug heroin is also an opioid. A health care provider may give you a prescription opioid to reduce pain after you have had a major injury or surgery.
2nd question- Prescription CNS depressants are medicines that can slow brain activity to treat anxiety and sleep disorders. ... Prescription CNS depressant use or misuse can lead to a substance use disorder, which takes the form of addiction in severe cases, even when used as prescribed by a doctor.
Hope I’ve helped ;)