Semi-conservative replication refers to A. each base bonding at the 1' position of the sugar. B. a purine always bonding to a pyrimidine. C. one helix strand that runs from the 5' to 3' direction and the other strand runs from the 3' to 5' direction. D. an original parent DNA strand and one newly synthesized DNA strand comprising a new DNA molecule. E. None of the choices is correct.