Black coat color in horses is conferred by the presence of a dominant B allele. Chestnut horses are genotype bb. A population of wild horses consists of 226 black horses and 28 chestnut horses. Assume that this population is at Hardy-Weinberg equilibrium for this locus. Please round all answers correctly to 4 decimal digits. What is the frequency of the B allele? Answer:

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Answer:

Frequency of B allele is 0.6681

Explanation:

If p represents the frequency of dominant allele and q represents the frequency of  recessive allele, according to Hardy-Weinberg equilibrium:

p + q = 1

p² + 2pq + q² = 1

where p² = frequency of homozygous dominant genotype

q² = frequency of homozygous recessive genotype

2pq = frequency of heterozygous genotype

Given that number of recessive chestnut horse = 28

Total horses = 226 + 28 = 254

frequency of b² genotype = 28/254 = 0.1102

frequency of recessive b allele = √0.1102 = 0.3319

So, frequency of B allele =

1 - 0.3319 = 0.6681

Hence frequency of B allele is 0.6681

The frequency of the B allele is : 0.6681

Applying Hardy-Weinberg equilibrium

p = frequency of dominant allele

q = frequency of recessive allele

therefore  p + q = 1

Hardy -weinberg equilibrium  : p² + 2pq + q² = 1

where :

p² = frequency of h0m0zygous dominant genotype

q² = frequency of h0m0zygous recessive genotype

2pq = frequency of heterozygous genotype

Given that :

Recessive chestnut horse ( q ) = 28

Dominant horse ( p ) = 226

Therefore Total number of horses = P + q

                                    = 226 + 28 = 254

Next step : determine the frequency of recessive b allele

Frequency of b² genotype = Recessive horse / Total number of horses

                                            = 28 / 254

                                            = 0.1102

Hence the frequency of recessive b allele = [tex]\sqrt{0.1102}[/tex] = 0.3319

Given that the frequency of recessive b allele = 0.3319

Frequency of B allele = 1 - 0.3319

                                     = 0.6681

Hence we can conclude that the frequency of B allele is 0.6681

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