Answer: 10gtt/ml means that in 10 drops there is a ml of the solution.
Now, you need 1000ml in 8 hours, and want to know the correct rate of flow in drops per minute.
first, 8 hours are 8*60 = 480 minutes.
then you need to infuse 1000ml in 480 minutes, so if you infuse at a constant rate, you need to infuse 1000/480 = 2.083 ml/min.
And we know that 10 drops are equivalent to 1 ml, then 2.083*10= 20.8 drops are equivalent a 2.083 ml, rounding it up, you get 21 drops for the dose.
So the correct rate of flow will be 21 drops per minute.