A client is admitted to the emergency department with chest pain and doesn't respond to nitroglycerin. The health care team obtains an electrocardiogram and administers I.V. morphine. The health care provider also considers administering alteplase. This thrombolytic agent must be administered how soon after onset of myocardial infarction (MI) symptoms?

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15-08-2019
Health

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A client is admitted to the emergency department with chest pain and doesn't respond to nitroglycerin. The health care team obtains an electrocardiogram and administers I.V. morphine. The health care provider also considers administering alteplase. This thrombolytic agent must be administered how soon after onset of myocardial infarction (MI) symptoms?

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euden57 euden57 · Answer 1 · 2019-08-26T22:41:31+02:00

Answer:

Alteplase is a thrombolytic agent that is used for the treatment of acute myocardial infarction for lysis of coronary artery thrombi. It should be used as an infusion in the first 6 hours of the beginning of the anginal symptoms. For example if you are a person over 70 kilos, 100mg are applied, in a 90-minute regimen like this: starting with a bolus of 15 mg, followed by an infusion of 50 mg for 30 minutes and 35 mg for 60 minutes.