Answer:
B.- It is the volume of filtrate formed each minute by the combined activity of all 2 million glomeruli of the kidneys
Explanation:
The Glomerular Filtration Rate is used in a clinical context to determine the renal function at the glomeruli. Therefore, it measures the volume of filtrate formed by all the glomeruli.
It depends of the following factors,
- The hydrostatic pressure in the glomeruli capilar
- The hydrostatic pressure in the glomeruli Bowman capsule (renal unit of the where the filtration is done)
- Oncotic pressure in the glomeruli capilar (pressure exerted by the proteins in the blood)
Moreover, there are a few other factors that influence this rate. For example, any changes in the diameter of the afferent arterioles will have a direct impact in the Glomerular Filtration Rate. If the diameter enlarges, the resistance in the arterioles diminished, and therefore the Glomerular Filtration Rate increases. A second example is the ability of the membrane to allow substances to pass through is also crucial. If the membrane was not allowing an easy exchange, the rate would decrease.
