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In the hierarchy of levels of gene regulation, in what order do the following levels of regulation take place? (1) post-translational modification(2) RNA processing(3) transcription(4) chromatin remodeling(4)-(1)-(2)-(3)(4)-(3)-(2)-(1)(4)-(2)-(3)-(1)(1)-(3)-(2)-(4)(1)-(2)-(3)-(4)

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Answer:

(4)-(3)-(2)-(1)

Explanation:

Gene expression is regulated at many levels:

  • Chromatin remodeling regulation includes altered histone modifications such as methylation which can regulate gene expression (up or down).
  • Transcription is regulated via transcriptional factors and specificity factors such as repressors and activators.
  • RNA processing can be regulated through the alternative splicing (different introns can be excised and combinations of different exons connected)
  • post-translational modification refers to modification of proteins after being synthesized.

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