Respuesta :
Population change was a long term effect of the Spanish colonization because the Aztecs ruled around 250,000 people. Then after the invasion there was said to be 240,000 people killed, those people killed didn't actually die in the war they died from a disease called smallpox.
Answer: The fur trade became a lasting source of profit. American Indian cultures were replaced by Spanish culture. Spanish systems built to spread Christianity remain operational.