The answer is:
282 in³
Since the question is asking about the amount of space, we know we are dealing with volume.
the volume formula for a rectangular prism (which both boxes are since the dimensions of each are different) is:
Volume= Length x Width x Height
for the small box, the volume is
V = 8 x 6 x 2
V = 96 in³
for the large box, the volume is
V = 18 x 7 x 3
V = 378 in³
The volume of each box is the amount of space there is inside. If you are to put the smaller box into the larger box, the volume of the larger box will be decreased by the volume of the small box
378 in³ - 96 in³ = 282 in³
282 in³ is left inside the large box.
Hope this helps!