I believe that the question came with the following options:
deletion; nondisjunction; replication; transformation (let me know if i'm wrong!)
out of those the process least associated with genetic abnormalities is replication. However, this does not mean that there is no possibility of genetic abnormality, as there is also the case of replication slippage, which is a mistake during the process of replication. However, on the whole replication is comparatively reliable.
Among the other options we also have deletion - which is the name for a mistake during replication!
