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Which of the following is characteristic of the product of the p53 gene?
A) It causes cell death via apoptosis.
B) It speeds up the cell cycle.
C) It allows cells to pass on mutations due to DNA damage.
D) It slows down the rate of DNA replication by interfering with the binding of DNA polymerase.
E) It is an activator for other genes.

Respuesta :

the correct answer is E) It is an activator for other genes.

abbusaicharan02

E) It is an activator for other genes and is characteristic of the product of the p53 gene.

Which genes are activated by p53?

It is an activator of other genes and is characteristic of the product of the p53 gene. Several pro-apoptotic BCL-2 family members, including.

BAX, 41, 42, 43, BBC3 (PUMA), 181 and PMAIP1 (NOXA), 182, are activated by p53. When released from mitochondria, cytochrome c binds to APAF1 and procaspase-9 to form apoptosomes. APAF1 is also activated by p53.

p53 is a potent activator of genes involved in cellular senescence such as p21 and PAI-1, and p53-dependent activation of these genes is an in vivo physiological response to DNA damage. Is shown [35, 57-60].

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