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Animal self-administration experiments and studies of drug choice among humans indicate that "short-acting barbiturates are more likely to lead to dependence than any of the benzodiazepines".

A barbiturate is a medication that goes about as a central nervous system depressant, and can in this manner create a wide range of impacts, from gentle sedation to death. The name barbiturate comes from the way that they are largely compound derivatives of barbituric acid.  

Benzodiazepines improve the impact of the neurotransmitter gamma-aminobutyric acid at the GABAA receptor, bringing about soothing, trancelike, anxiolytic (against nervousness), anticonvulsant, and muscle relaxant properties.