Explain how consuming and acid neutralizing antacid might affect protein digestion. Apply the concept of activation energy ti support your explanation

Respuesta :

In the stomach, the enzyme pepsin has the function to break proteins into smaller units-polypeptides. Pepsin is synthesized and secreted in an inactive form- pepsinogen. Activation energy (the minimum amount of energy that is required to activate an enzyme) is achieved in the acidic medium (pH from 1 to 3). So, the activation of pepsin (conversion of pepsinogen to pepsin) is possible thanks to the cells in the stomach lining which produce hydrochloric acid (HCl), causing the stomach contents to have a low pH.


Antacids neutralize the acid made by the stomach, affecting the digestion.


The acidic environment of stomach is important for proteiase enzymes to activate and work.

Activation Energy:

It is the energy required by enzyme to convert into functional form or to activate.

  • For example:  the protein found in stomach Pepsinogen convert to pepsin(active form) in the acidic environment and breakdown protein.

When Antacid neutralize the stomach acidic environment, the conversion of Pepsinogen to pepsin stops. hence protein digestion decreased.

Hence we can say that the acidic environment of stomach is important for proteiase enzymes to activate and work.

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