Major survival surgery on non-rodent mammals
Major survival surgery in non-rodent mammals must be conducted in dedicated facilities. Major survival
surgery penetrates and exposes a body cavity, produces substantial impairment of physical or physiologic
functions, orinvolves extensive tissue dissection ortransection (e.g., laparotomy, thoracotomy, joint
replacement, and limb amputation). The ultimate decision to classify a surgery as major or minor will be
made by the IACUC. Investigators cannot perform major survival surgery in non-rodent mammals in their
own laboratories, but must make use of IACUC approved survival surgery suites that meet federal standards.
Major operative procedures on non-rodents will be conducted only in facilities intended forthat purpose
which shall be operated and maintained under aseptic conditions. Dedicated surgery suites must be
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approved by the IACUC priorto use and inspected semi-annually. Contact the IACUC office for additional
details regarding dedicated surgical suites and major versus minor surgical classifications.
