The main difference between weather and climate is that ________. climate is the daily variations that actually occur at a location and weather is the general pattern of climate over time climate is a political opinion while weather is reality. climate is the regional pattern based on latitude and humidity while weather is the daily pattern based on season. weather is the regional pattern based on latitude and humidity while climate is the daily pattern based on season. weather is the daily variations that actually occur at a location and climate is the general pattern of weather over time