Mixing substances can cause physical and chemical changes. Sometimes, mixing substances results in the creation of new substances. Which of these examples provides the best evidence of a new substance being made? A Three substances are mixed in a sealed plastic bag. The reaction results in the mixture becoming warm, expanding, and changing color. B Two substances are stirred together in a beaker and left untouched for one day. The substances separated into two layers in the beaker. A packet of powdered drink mix, one cup of sugar, and two quarts of water are mixed in a pitcher. The stirring causes the water to turn purple. * C D A bottle of aspirin pills are crushed into powder and mixed with sand in a plastic container. Water is added to the mixture to dissolve the aspirin.​