A female client is prescribed donepezil (Aricept), a cholinesterase inhibitor. She complains of GI distress, anorexia, and weight loss. What should the health care practitioner know about these side effects?
1) Slow titration of dosage improves patient tolerance.
2) They are related to route of administration.
3) They are related to the time of day when medication is taken.
4) They are dose-related and irreversible.