A patient with acute limb ischemia undergoes a surgical procedure to remove an arterial blockage in the leg. Which of the following mechanisms is one of the most likely to contribute to tissue injury after the removal of the blockage?
A. Reduced concentration of calcium in the affected cells
B. Deposition of certain forms of antibodies that will lead to complement activation
C. Decreased recruitment of inflammatory cells to the site
D. Increased oxygen reduction in mitochondria