All are adverse effects that can occur with use of tetracycline except which of the following?
1) Photosensitivity
2) Permanent discoloration of teeth if taken after development
3) Permanent discoloration of teeth and bones if taken during period of development
4) Gastrointestinal problems, including anorexia, nausea, vomiting, and diarrhea
5) Hepatotoxicity if given by intravenous administration, especially during pregnancy