What is the biochemical target of the aminoglycosides, and why do they show -cidal activity given this target?
a) Cell wall synthesis; they disrupt the integrity of the cell membrane
b) Protein synthesis; they inhibit ribosomal function, leading to cell death
c) Nucleic acid synthesis; they interfere with DNA replication and transcription
d) Cell membrane integrity; they disrupt membrane potential, causing cell lysis