In a 65-year-old patient undergoing VATS (Video-Assisted Thoracic Surgery) for lower lobectomy, one lung ventilation is required. What is a major risk factor for hypoxemia?
a. A large central vs. smaller peripheral lesion
b. Right-sided surgery
c. Left-sided surgery
d. Small alveolar-arterial oxygen gradient on two-lung ventilation E. Lateral vs. supine positioning