A 48-year-old woman with Stage III ER+, Her-2 negative breast cancer is completing her second year of treatment with tamoxifen. At a recent follow-up with her oncologist, the patient expresses concerns about her changes in mood and requests an antidepressant. Which of the following is the safest antidepressant to initiate in this patient?
A. Paroxetine
B. Citalopram
C. Fluoxetine
D. Bupropion
E. Duloxetine