When you treat ectopic pregnancy with medical management with methotrexate, what is the criteria? What is the most common side effect of this treatment? And what do you assume if this side effect occurs? What is the failure rate of methotrexate?
a) Serum β-hCG <5000 mIU/mL, No fetal cardiac activity, No rupture; Nausea and Vomiting; Ectopic rupture; 10%
b) Serum β-hCG >10,000 mIU/mL, Fetal cardiac activity, Rupture; Abdominal pain; Infection; 5%
c) Serum β-hCG 5000-10,000 mIU/mL, No fetal cardiac activity, No rupture; Hair loss; Liver toxicity; 15%
d) Serum β-hCG <5000 mIU/mL, No fetal cardiac activity, Rupture; Headache; Renal failure; 20%