Which of the following events occur during fertilization? 1. Acrosomal enzymes are released directly into the secondary oocyte, causing the cortical reaction 2. When the nucleus of the sperm enters the secondary cocyto the oocyte is stimulated to conclude moois before the two nucleituda: 3. The sperm first makes contact with the zone pellucide 4. Intracellular levels of Ca2+ decline, leading to the exocytosis of cortical granules and the removal of the colonia todista.A. Only 1 B. 1, 2 and 4 C. 1, 2 and 3 D. 2 and 3